Methanol → HCID 12274826, compound

HRID 1657468Notes

Reaction equation

HRID 1657468 reaction equation
[Br:1][CH:2]1[CH:11](Br)[C:7]2[S:8][CH:9]=[CH:10][C:6]=2[C:5](=[O:13])[C:4]2[CH:14]=[CH:15][CH:16]=[CH:17][C:3]1=2.[CH3:18][OH:19]>>[Br:1][CH:2]1[CH:11]([O:19][CH3:18])[C:7]2[S:8][CH:9]=[CH:10][C:6]=2[C:5](=[O:13])[C:4]2[CH:14]=[CH:15][CH:16]=[CH:17][C:3]1=2

Participants

3

Reactant 2

HCID 887MethanolHCID 2780821AC1Mcynq

Product 1

HCID 12274826HCID 12274826, compound

Procedure

A suspension of 20 g of 9,10-dibromo-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one in 400 cc of methanol is boiled at reflux for 5 hours. 9-Bromo-9,10-dihydro-10-methoxy-4H-benzo[ 4,5]cyclohepta[1,2-b]thiophen-4-one (M.P. 103°-106°) is obtained.

Workup

  1. temperatureat reflux for 5 hours

Sources & evidence

ORD record
ord-93298ee647d64582871a273fa59fc4cf
Source dataset
uspto-grants-1976_06
Patent number
US03960894

Reaction notes

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