Trifluoroacetic acid → HCID 68138499, compound

Participants

Reaction Steps

To 25 ml. of well stirred trifluoroacetic acid, 5.35 g. of 4-(p-fluoro-o-tolyl)-4-hydroxycyclohexanone (obtained as in Example 47) is added. After about 10 minutes, the mixture is poured into an excess of aqueous sodium bicarbonate solution and the material that precipitates is extracted with ether. The extract is washed with aqueous sodium bicarbonate solution, water and brine and then evaporated to dryness to give 4(p-fluoro-o-tolyl)-3-cyclohexen-1-one.

Provenance & Evidence