Ethanol → HCID 68127629, compound

Participants

Reaction Steps

2-Methoxy-6-methylsulphonyl-9-oxaphenothiazine (m.p. higher than 280°C.; 48 g.) is prepared by oxidation of 2-methoxy-6-methylthio-10-acetylphenothiazine (m.p. 106°-108°C.; 55.0 g.) dissolved in 95% ethanol (95 cc.) by means of 130 volumes hydrogen peroxide (842 cc.). The crude 2-methoxy-6-methylsulphonyl-9-oxo-10-acetylphenothiazine obtained (m.p. about 160°C.) is saponified by means of an alcoholic solution of potassium hydroxide (11.2 g.) in ethanol (200 cc.).

Provenance & Evidence