HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidineethanol → HCID 54509260, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidineethanol | HCID 73953 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 21534859 | HCID 21534859 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 54509260 | HCID 54509260 | 36.7% |
Reaction Conditions
| Temperature | 150 °C |
|---|
Reaction Steps
A mixture of 2-isopropoxy-6-methylsulphonyl-10-(3-chloropropyl)phenothiazine (20 g.), 4-hydroxyethylpiperidine (6.4 g.) and sodium bicarbonate (16.5 g.) in dimethylformamide (170 cc.) is heated at 150°C. for 7 hours 30 minutes with stirring. The reaction mixture is then treated under the conditions mentioned in Example 1. 2-Isopropoxy-6-methylsulphonyl-10-[3-(4-hydroxyethylpiperidino)propyl]phenothiazine (9.0 g.), melting at about 50°C., is thus obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03961055 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-d50849881ca64b6facb50aa99b77d854 |
| Source note | uspto-grants-1976_06 |