2-Piperidone → HCID 22754294, compound

HRID 1657796Notes

Reaction equation

[CH:1]1[C:14]2[NH:13][C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[O:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[NH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][C:16]1=O.P(Cl)(Cl)([Cl:24])=O>>[ClH:24].[N:15]1[CH2:20][CH2:19][CH2:18][CH2:17][C:16]=1[N:13]1[C:14]2[CH:1]=[CH:2][CH:3]=[CH:4][C:5]=2[O:6][C:7]2[C:12]1=[CH:11][CH:10]=[CH:9][CH:8]=2

Participants

Reactant 3

HCID 126652-Piperidone

HCID 24813Phosphorus oxychloride

HCID 67278Phenoxazine

Product 1

HCID 22754294HCID 22754294, compound

Procedure

Reaction of phenoxazine, 2-piperidone, and phosphorus oxychloride according to the procedure of Example 1 provides 10-(3,4,5,6-TETRAHYDRO-2-PYRIDYL)PHENOXAZINE HYDROCHLORIDE, m.p. 218.5°-221°C. (corr.), in a 27% overall yield from absolute ethanol.

Sources & evidence

ORD record: ord-d23e871f6a4d414d9ede9c0c6a8728cf
Source dataset: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03962252

Reaction notes

Loading…