Acridan → 10-(Isopropyliminomethyl)acridan

HRID 1657798Notes

Reaction equation

[CH:1]1[C:14]2[CH2:13][C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[NH:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH:15]([NH:18][CH:19]=O)([CH3:17])[CH3:16].P(Cl)(Cl)(Cl)=O>>[CH:15]([N:18]=[CH:19][N:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:13][C:14]2[CH:1]=[CH:2][CH:3]=[CH:4][C:5]1=2)([CH3:17])[CH3:16]

Participants

Reactant 3

HCID 7106Acridan

HCID 24813Phosphorus oxychloride

HCID 268118N-(propan-2-yl)formamide

Product 1

HCID 304416510-(Isopropyliminomethyl)acridan

Procedure

Reaction of acridan, isopropylformamide and phosphorus oxychloride accoridng to the procedure of Example 1 provides the free base 10-[(ISOPROPYLIMINO)METHYL]ACRIDAN, m.p. 149.5°-150.5°C. (corr.), from n-hexane.

Sources & evidence

ORD record: ord-ab858ac4211d460da13e61317faf2db1
Source dataset: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03962252

Reaction notes

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