Formaldehyde → HCID 21530331, compound

Participants

Reaction Steps

A mixture of 25 parts of 4-n-hexylcarbamoyl-2,2,7,7-tetramethyl-1,4-diazacycloheptan-5-one, 11.2 parts of sodium formate, 25 parts of formaldehyde and 2 parts of formic acid were heated at steam bath temperature for 2 hours. 250 Parts of ammonium hydroxide were then added and the solution extracted with chloroform to yield, after drying, 20 parts of a heavy oil which was further purified by column chromatography (silica) to give pure 4-n-hexylcarbamoyl-1,2,2,7,7-pentamethyl-1,4-diazacycloheptan-5-one. This material had the following elemental analysis by weight:

Provenance & Evidence