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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1657852Generated: November 3, 2026

Hydrochloric Acid → HCID 21506809, compound

https://huagongshe.com/reaction/1657852

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-Hydroxy-4-(alpha-hydroxy-4-trifluoromethyl-2-tolyl)-1-methylpiperidineHCID 86733526—
ProductHCID 21506809HCID 21506809—

Reaction Steps

Treatment of 4-hydroxy-4-(α-hydroxy-4-trifluoromethyl-2-tolyl)-1-methylpiperidine with hydrochloric acid by the method described in Example 16d provides 1,3-dihydro-1'-methyl-6-trifluoromethylspiro[isobenzofuran-1,4'-piperidine].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03962259
Source datasetuspto-grants-1976_06
ORD IDord-9e703be7e72b4721bfba08501dbdf5a0
Source noteuspto-grants-1976_06