Bromine → HCID 21531338, compound

HRID 1657924Notes

Reaction equation

HRID 1657924 reaction equation
[CH2:1]([C:5]1[CH:12]=[CH:11][C:10]([CH:13]([CH3:15])[CH3:14])=[CH:9][C:6]=1[CH2:7][Cl:8])[CH:2]([CH3:4])[CH3:3].[Br:16]Br>[Fe].C(Cl)(Cl)(Cl)Cl>[Br:16][C:11]1[C:10]([CH:13]([CH3:15])[CH3:14])=[CH:9][C:6]([CH2:7][Cl:8])=[C:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[CH:12]=1

Participants

5

Reactant 2

HCID 24408BromineHCID 21531284HCID 21531284, compound

Product 1

HCID 21531338HCID 21531338, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 5943Carbon TetrachlorideSolvent2×

Procedure

In a flask are placed 225 parts of 2-isobutyl-5-isopropylbenzyl chloride, 300 parts of carbon tetrachloride and 2.5 parts of iron powder. Bromine (160 parts) in 100 parts of carbon tetrachloride is added dropwise during 7 hr. The solution is washed twice with hydrochloric acid then with sodium bicarbonate solution, dilute sodium bisulfite solution, and water. The solution is dried, the carbon tetrachloride removed, and the 4-bromo-2-isobutyl-5-isopropylbenzyl chloride distilled under reduced pressure.

Workup

  1. customIn a flask are placed
  2. washThe solution is washed twice with hydrochloric acid
  3. customThe solution is dried
  4. customthe carbon tetrachloride removed
  5. distillationthe 4-bromo-2-isobutyl-5-isopropylbenzyl chloride distilled under reduced pressure

Sources & evidence

ORD record
ord-f654a8dae8f64cb5951bf2299fba2b61
Source dataset
uspto-grants-1976_06
Patent number
US03962307

Reaction notes

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