Hydrochloric Acid → HCID 21532396, compound

Participants

Reaction Steps

100 g of 2-acetoxyethyl-methyl phosphinic acid n-octyl ester are heated to 65°-70°C in 200 ml of methanol containing 0.5 wt.% of HCl, while simultaneously removing by distillation a mixture of methyl acetate/methanol. After distillation under reduced pressure 70 g of 2-hydroxyethyl-methyl-phosphinic acid-n-octyl ester (b.p. 139°C/0.2 torr) are obtained, corresponding to a yield of 82.5% of the theoretical.

Provenance & Evidence