Potassium thiocyanate → HCID 21532596, compound

Participants

Reaction Steps

46.5 g of 2-trifluoromethyl-4-chloro-quinazoline is added, while stirring, to a mixture of 97 g of potassiumthiocyanate and 200 ml of acetic acid. The reaction mixture is stirred for 2 hours at room temperature, the resultant light-yellow precipitate is drawn off, consecutively washed with a small amount of acetic acid and water and subsequently dried in air. The 2-trifluoromethyl-4-thiocyano-quinazoline thus obtained has a melting point of 134°-136°C.

Provenance & Evidence