Acetic Acid → HCID 12223721, compound

Participants

Reaction Steps

A mixture of 3.36 g. (0.01 mol.) of 10-trifluoromethyl-1H-pyrimido[5,4,3-kl]phenothiazine-1,3(2H)-dione and three equivalents of 30% hydrogen perioxide in 70 ml. of glacial acetic acid was heated at 75°-85° for 4 hours. The reaction mixture was cooled and diluted with water. The precipitated product was collected by filtration and washed with water to give the title compound, m.p. 290 -293° (methanol).

Provenance & Evidence