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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1658129Generated: October 30, 2026

Iodoethane → 2-(4'-Benzyl-piperazino)-5-oxo-6-carbethoxy-8-ethyl-5,8-dihydro-pyrido(2,3-d)pyrimidine

https://huagongshe.com/reaction/1658129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
ReactantEthyl 2-(4-benzyl-1-piperazinyl)-5-ethoxypyrido[2,3-d] pyrimidine-6-carboxylateHCID 21532581—
Product2-(4'-Benzyl-piperazino)-5-oxo-6-carbethoxy-8-ethyl-5,8-dihydro-pyrido(2,3-d)pyrimidineHCID 12266808—

Reaction Steps

Following the procedure described in Example 37 using ethyl 2-(4-benzyl-1-piperazinyl)-5-ethoxypyrido[2,3-d] pyrimidine-6-carboxylate with ethyl iodide, there is obtained the product, m.p. 151° - 153°C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03962443
Source datasetuspto-grants-1976_06
ORD IDord-0825fcae53294580be8315f70fd9c60f
Source noteuspto-grants-1976_06