2-Bromoethanol → HCID 15574554, compound

HRID 1658131Notes

Reaction equation

HRID 1658131 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[N:9]=[CH:10][C:11]3[C:17]([O:18]CC)=[C:16]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH:15]=[N:14][C:12]=3[N:13]=2)[CH2:4][CH2:3]1.[CH2:26](Br)[CH2:27][OH:28]>>[OH:28][CH2:27][CH2:26][N:14]1[C:12]2[N:13]=[C:8]([N:5]3[CH2:4][CH2:3][N:2]([CH3:1])[CH2:7][CH2:6]3)[N:9]=[CH:10][C:11]=2[C:17](=[O:18])[C:16]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:15]1

Participants

3

Reactant 2

HCID 108982-BromoethanolHCID 21532573HCID 21532573, compound

Product 1

HCID 15574554HCID 15574554, compound

Procedure

Following the procedure described in Example 37 using ethyl 2-(4-methyl-1-piperazinyl)-5-ethoxypyrido-[2,3-d]pyrimidine-6-carboxylate with ethylenebromohydrine, there is obtained the product, m.p. 197 - 199°C.

Workup

  1. customthere is obtained the product, m.p. 197 - 199°C.

Sources & evidence

ORD record
ord-991d3a91b87b49c48710e2082118cd0a
Source dataset
uspto-grants-1976_06
Patent number
US03962443

Reaction notes

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