反应详情

2-Phenylamino-N-(2-methyl-4-sulphamoylphenyl)-acetamide (16 g) was dissolved in ethano, (320 ml) and paraformaldehyde (1.9 g) in water (640 ml) added. The mixture was refluxed 11/2 hr, cooled and filtered. The residue was crystallised from DMF/water to yield 16 g, m.p. 206°-210°.

1. additionadded
2. temperatureThe mixture was refluxed 11/2 hr
3. temperaturecooled
4. filtrationfiltered
5. customThe residue was crystallised from DMF/water
6. customto yield 16 g, m.p. 206°-210°