Ethanol → Benzenesulfonamide, 4-(5-oxo-3-phenyl-1-imidazolidinyl)-2-(trifluoromethyl)-

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Reaction Steps

2-Phenylamino-N-(3-trifluoromethyl-4-sulphamoylphenyl)-acetamide (11.2g) was added to ethanol (200 ml) and paraformaldehyde (1.3g) in water (400 ml) added thereto under reflux. The mixture was refluxed 11/2 hr, cooled and worked up as in Example 6(c) to yield 11,8 g, m.p. 235°-238°.

Provenance & Evidence