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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1658218Generated: November 2, 2026

Ethanol → Benzenesulfonamide, 3-chloro-4-(3-(4-methoxyphenyl)-5-oxo-1-imidazolidinyl)-

https://huagongshe.com/reaction/1658218

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantFormaldehydeHCID 712—
ReactantHCID 21528835HCID 21528835—
SolventWaterHCID 962—
ProductBenzenesulfonamide, 3-chloro-4-(3-(4-methoxyphenyl)-5-oxo-1-imidazolidinyl)-HCID 3041011—

Reaction Steps

The product of stage a) (15g) was dissolved in ethanol (200 ml) and treated with paraformaldehyde (2.5g) in water (400 ml). The mixture was refluxed for 3 hours, cooled in ice/water and filtered to yield the title product (5 g), m.p. 221°-223°

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03963706
Source datasetuspto-grants-1976_06
ORD IDord-8f4ca76e6cc94683a5126b83062eb037
Source noteuspto-grants-1976_06