Cyclohexylamine → HCID 2990118, compound

HRID 1658221Notes

Reaction equation

HRID 1658221 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-:14])=[O:13])=[CH:8][CH:7]=1)=[O:4].[CH:15]1([NH2:21])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>C(OCC)(=O)C.O>[CH:15]1([NH:21][CH2:2][C:3]([NH:5][C:6]2[CH:11]=[CH:10][C:9]([N+:12]([O-:14])=[O:13])=[CH:8][CH:7]=2)=[O:4])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

4

Reactant 2

HCID 7965CyclohexylamineHCID 140220Acetanilide, 2-chloro-4'-nitro-

Product 1

HCID 2990118HCID 2990118, compound

Reagents, catalysts & solvents 1

HCID 22728543Water ethylacetateSolvent

Procedure

2-Chloro-N-(4-nitrophenyl)-acetamide (11.5g) and cyclohexylamine (10.7g) were heated together 2 hours at 150° and then added to ethyl acetate/water. The product was extracted with ethyl acetate to yield 9.0g, m.p. 123°-125°C.

Workup

  1. extractionThe product was extracted with ethyl acetate
  2. customto yield 9.0g, m.p. 123°-125°C.

Sources & evidence

ORD record
ord-07e88519ab6c47b38a4a6d0df4dc7220
Source dataset
uspto-grants-1976_06
Patent number
US03963706

Reaction notes

Loading…