Sulfanilamide → HCID 21528866, compound

HRID 1658231Notes

Reaction equation

HRID 1658231 reaction equation
Cl[CH2:2][C:3]([NH:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:4].[S:12]([NH2:22])(=[O:21])([C:14]1[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=1)=[O:13].[OH-].[Na+]>>[S:12]([C:14]1[CH:19]=[CH:18][C:17]([NH:20][CH2:2][C:3]([NH:5][CH:6]2[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)=[O:4])=[CH:16][CH:15]=1)(=[O:13])(=[O:21])[NH2:22]

Participants

4

Reactant 3

HCID 5333SulfanilamideHCID 14798Sodium HydroxideHCID 2223652-Chloro-N-cyclohexylacetamide

Product 1

HCID 21528866HCID 21528866, compound

Procedure

2-Chloro-N-cyclohexylacetamide (8.7 g) and sulfanilamide (17.2g) were heated for 30 min. at 160°C. The mixture was then added to 2N NaOH and extracted with ethyl acetate to yield 8.2 g, product, m.p. 223° - 225°C

Workup

  1. extractionextracted with ethyl acetate
  2. customto yield 8.2 g, product, m.p. 223° - 225°C

Sources & evidence

ORD record
ord-b3ccd198d17649e7bf02798452bfa3e8
Source dataset
uspto-grants-1976_06
Patent number
US03963706

Reaction notes

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