反应详情

A mixture of 8.2 parts of α-(aminomethyl)-m-methylbenzyl alcohol, 6.1 parts of 2-(nitramino)-2-imidazoline and 40 parts of xylene is stirred in an oil-bath at 150°-160°C, while almost all xylene is distilled off. The residue is diluted with a few parts of acetone and allowed to crystallize. The product is filtered off and recrystallized from 4-methyl-2-pentanone, yielding α-(2-imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol; m.p. 121°C.

1. distillationwhile almost all xylene is distilled off
2. additionThe residue is diluted with a few parts of acetone
3. customto crystallize
4. filtrationThe product is filtered off
5. customrecrystallized from 4-methyl-2-pentanone