反应详情

To a solution of 40 g. of 2,3-dihydro-5-benzofuranamine in 200 ml. of methanol is added 23 ml. of isopropyl iodide and 35 ml. of triethylamine. The solution is refluxed for 55 hours and then concentrated in vacuo. The resultant oil is extracted several times with diethyl ether, the extract combined, filtered through Celite, and the ether removed in vacuo to obtain an oil of N-isopropyl-2,3-dihydro-5-benzofuranamine.

1. temperatureThe solution is refluxed for 55 hours
2. concentrationconcentrated in vacuo
3. extractionThe resultant oil is extracted several times with diethyl ether
4. filtrationfiltered through Celite
5. customthe ether removed in vacuo