Formaldehyde → HCID 21528955, compound

Participants

Reaction Steps

To a stirred solution of 4.6 g. of 1-isopropyl-3,4,7,8-tetrahydro-4-phenyl-furo[2,3-g]quinazolin-2(1H)-one in 200 ml. of dioxane cooled to 5°±5°C. is added dropwise a solution of 3.0 g. of potassium permanganate in 140 ml. of water. After the addition is completed 1.5 ml. of formalin solution is added. The resulting precipitated solids are removed by filtration and the filtrate concentrated in vacuo to obtain an oil of 1-isopropyl-7,8-dihydro-4-phenyl-furo[2,3-g]quinazolin-2(1H)-one.

Provenance & Evidence