HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → N-isopropyl-2,3-dihydro-6-benzofuranamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | 2,3-Dihydro-1-benzofuran-6-amine | HCID 12369044 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | N-isopropyl-2,3-dihydro-6-benzofuranamine | HCID 21528943 | — |
Reaction Steps
To a solution of 2.8 g. of 2,3-dihydro-6-benzofuranamine in 150 ml. of methanol is added 18 ml. of isopropyl iodide and 26.5 ml. of triethylamine. The solution is refluxed for 60 hours and then concentrated in vacuo. The resultant oil is extracted repeatedly with diethyl ether. The extracts are combined, filtered through Celite, and the ether removed in vacuo to give an oil of N-isopropyl-2,3-dihydro-6-benzofuranamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03963717 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-a51d9ac27980474b8dd4ba0d8f526425 |
| Source note | uspto-grants-1976_06 |