反应详情

To a solution of 2.8 g. of 2,3-dihydro-6-benzofuranamine in 150 ml. of methanol is added 18 ml. of isopropyl iodide and 26.5 ml. of triethylamine. The solution is refluxed for 60 hours and then concentrated in vacuo. The resultant oil is extracted repeatedly with diethyl ether. The extracts are combined, filtered through Celite, and the ether removed in vacuo to give an oil of N-isopropyl-2,3-dihydro-6-benzofuranamine.

1. temperatureThe solution is refluxed for 60 hours
2. concentrationconcentrated in vacuo
3. extractionThe resultant oil is extracted repeatedly with diethyl ether
4. filtrationfiltered through Celite
5. customthe ether removed in vacuo