反应详情

To a solution of 15 g. of 2,3-dihydro-7-benzofuranamine in 150 ml. of methanol is added 8.5 ml. of isopropyl iodide and 13.4 ml. of triethylamine. The solution is refluxed for 45 hours and then concentrated in vacuo. The resulting oil is extracted several times with diethyl ether, the ether extracted combined filtered through Celite, and the ether removed in vacuo to obtain an oil of N-isopropyl-2,3-dihydro-7-benzofuranamine.

1. temperatureThe solution is refluxed for 45 hours
2. concentrationconcentrated in vacuo
3. extractionThe resulting oil is extracted several times with diethyl ether
4. extractionthe ether extracted
5. filtrationcombined filtered through Celite
6. customthe ether removed in vacuo