Acetone → 2,2,6,6-Tetramethyl-4-piperidone

Participants

Reaction Conditions

Reaction Steps

A solution of 19.2 g. of acetonine in 70 g. of acetone was added with 7 g. of methanol. Then, 0.9 g. of dry gaseous hydrogen chloride was introduced therein and absorbed. The solution was sealed and heated at 60°C. for 10 hours to effect the reaction. After completion of the reaction, the reaction mixture was purified in the same manner as in Example 1 to obtain triacetonamine in a yield of 140%.

Provenance & Evidence