Malonic Acid → 2,2,6,6-Tetramethyl-4-piperidone

Participants

Reaction Steps

A solution of 6.3 g. of acetonine in 40 g. of acetone was added with 0.5 g. of malonic acid and the mixture was heated at 60°C. for 10 hours in a sealed equipment to effect the reaction. After completion of the reaction, the reaction mixture was purified in the same manner as in Example 1 to obtain triacetonamine in a yield of 115%.

Provenance & Evidence