Acetone → 2,2,6,6-Tetramethyl-4-piperidone

Participants

Reaction Conditions

Reaction Steps

A solution of 5.0 g. of acetonine in a mixed solvent comprising 19 g. of acetone and 1.9 g. of methanol was added with 1.5 g. of triacetonamine hydrochloride. The mixture was heated at 60°C. for 10 hours in a sealed equipment to effect the reaction. After completion of the reaction, the reaction mixture was purified in the same manner as in Example 1 to obtain triacetonamine in a yield of 115% deducting the amount of triacetonamine used as catalyst.

Provenance & Evidence