Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | Ethyl 8-ethoxy-2H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylate | HCID 12367717 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 3504015 | HCID 3504015 | 98.6% |
Reaction Steps
A mixture containing 25 ml of toluene, 5 g of ethyl 4-ethoxy-6,7-methylenedioxyquinoline-3-carboxylate and 5.67 g of ethyl bromide was placed in a sealed tube and heated at 130°C (bath temperature) for 30 hours. The reaction mixture was worked up as described in Example 9 and 4.93 g of ethyl 1-ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylate was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03963736 |
|---|
| Source dataset | uspto-grants-1976_06 |
|---|
| ORD ID | ord-91f6dec8dffe4e25bdf29676b5e76d4a |
|---|
| Source note | uspto-grants-1976_06 |
|---|
