Toluene → HCID 3504015, compound

HRID 1658346Notes

Reaction equation

HRID 1658346 reaction equation
C([O:3][C:4]1[C:13]2[C:8](=[CH:9][C:10]3[O:16][CH2:15][O:14][C:11]=3[CH:12]=2)[N:7]=[CH:6][C:5]=1[C:17]([O:19][CH2:20][CH3:21])=[O:18])C.[C:22]1(C)C=CC=C[CH:23]=1>>[CH2:22]([N:7]1[C:8]2[C:13](=[CH:12][C:11]3[O:14][CH2:15][O:16][C:10]=3[CH:9]=2)[C:4](=[O:3])[C:5]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:6]1)[CH3:23]

Participants

3

Reactant 2

HCID 1140TolueneHCID 12367717Ethyl 8-ethoxy-2H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylate

Product 1

HCID 3504015HCID 3504015, compound

Procedure

A melt of 5 g of ethyl 4-ethoxy-6,7-methylenedioxyquinoline-3-carboxylate was heated at 220°C for 7 hours and then cooled. The product was thinned with toluene, filtered and recrystallized from chloroform petroleum ether to provide 3.7 g of ethyl 1-ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylate as needles, m.p. 177°-178°C.

Workup

  1. temperaturecooled
  2. filtrationfiltered
  3. customrecrystallized from chloroform petroleum ether

Sources & evidence

ORD record
ord-e2b380fc8adb4a44b68f483c513f17ed
Source dataset
uspto-grants-1976_06
Patent number
US03963736

Reaction notes

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