HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21527616, compound → HCID 21527623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21527616 | HCID 21527616 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21527623 | HCID 21527623 | — |
Reaction Steps
5 g of 4-[3-(N-benzyl-tert-butylamino)-2-nicotinoyloxypropoxy]oxindole are debenzylated with hydrogen in 25 cc of tetrahydrofuran, in the presence of 1 g of a palladium catalyst (10% of palladium on charcoal). The title compound is obtained, the dihydrochloride thereof having a M.P. of 215°-218°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03965095 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-471c912e12c14d8ca754b683ea02fac4 |
| Source note | uspto-grants-1976_06 |