HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylpyridine → 3-Phenylpyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylpyridine | HCID 13886 | — |
| Reactant | Sodium amide | HCID 24533 | — |
| Product | 3-Phenylpyridin-2-amine | HCID 2762795 | — |
Reaction Steps
2-Amino-3-phenylpyridine is prepared by reacting 46.5 g. 3-phenylpyridine with 11.7 g. of sodium amide at a temperature of 250° in the presence of mineral oil. The 2-amino-3-phenylpyridine that is formed is purifed by distillation and is substituted for the 2-amino-4-phenylpyridine in Example 8 to obtain the named compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03965100 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-e44c6ce050e842c38e7ea1dad8dccada |
| Source note | uspto-grants-1976_06 |