Ethyl Bromide → 2-Aminonicotinic acid

HRID 1658510Notes

Reaction equation

HRID 1658510 reaction equation
[NH2:1][C:2]1[N:10]=[CH:9][CH:8]=[C:7](O)[C:3]=1[C:4]([OH:6])=[O:5].C(Br)C>>[NH2:1][C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 6332Ethyl BromideHCID 178508410HCID 178508410, compound

Product 1

HCID 729302-Aminonicotinic acid

Procedure

By substituting 2-amino-4-ethoxynicotinic acid (prepared by reaction of the 2-amino-4-hydroxynicotinic acid with ethyl bromide in accordance with the procedure of Yale and Pluscec, supra.) for the 2-aminonicotinic acid in Example 4, there is obtained the named compound.

Sources & evidence

ORD record
ord-d3327c79dac347bcbfcac6ac3de45c1f
Source dataset
uspto-grants-1976_06
Patent number
US03965100

Reaction notes

Loading…