Hydrochloric Acid → HCID 131710342, compound

HRID 1658513Notes

Reaction equation

HRID 1658513 reaction equation
[C:1]1([CH2:7][O:8][C:9]2[C:14]3=[N:15][C:16]4[CH2:22][CH2:21][CH2:20][C:17]=4[C:18](=[O:19])[N:13]3[CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:23]>CCOCC>[ClH:23].[C:1]1([CH2:7][O:8][C:9]2[C:14]3=[N:15][C:16]4[CH2:22][CH2:21][CH2:20][C:17]=4[C:18](=[O:19])[N:13]3[CH:12]=[CH:11][CH:10]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12354099HCID 12354099, compound

Product 1

HCID 131710342HCID 131710342, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 2.92 g. of 2,3-dihydro-5-(phenylmethoxy)cyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one in 25 ml of anhydrous ether, cooled externally by a wet ice bath, is added dropwise and with stirring, 10 ml of a N-ethereal hydrogen chloride solution. The salt separates spontaneously. It is filtered and recrystallized from anhydrous 2-propanol-ether to give the named compound as colorless needles.

Workup

  1. additionis added dropwise
  2. filtrationIt is filtered
  3. customrecrystallized from anhydrous 2-propanol-ether

Sources & evidence

ORD record
ord-8a9176ec3ea148cbb8716dc34b81d61b
Source dataset
uspto-grants-1976_06
Patent number
US03965100

Reaction notes

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