Benzyl Bromide → HCID 13397856, compound

Participants

Reaction Steps

Triethylamine (approximately 3 ml) is added to a slurry of 5.0 g of 4,6-dimethylisothiazolo-(5,4-b)-pyridin-3(2H)-one in 120 ml reagent grade acetone until the mixture becomes homogeneous. A solution of 4.0 g (0.024 m) of benzyl bromide in 20 ml acetone is then added. The reaction mixture is stirred for 3 days at room temperature and is then stripped to dryness. The residue is washed once with deionized water, then with 95% 2B ethanol, then ether and dried to give the product.

Provenance & Evidence