Hydrochloric Acid → HCID 10657374, compound

HRID 1658580Notes

Reaction equation

HRID 1658580 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][CH:10]=2)[CH:5]=[CH:4][C:3]=1[N+:16]([O-])=O.Cl>>[NH2:16][C:3]1[CH:4]=[CH:5][C:6]([O:8][C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][CH:10]=2)=[CH:7][C:2]=1[NH2:1]

Participants

3

Reactant 2

HCID 313Hydrochloric Acid2×HCID 10563608HCID 10563608, compound

Product 1

HCID 10657374HCID 10657374, compound

Procedure

1.2 G. of 2-amino-4-(p-chlorophenoxy)-1-nitrobenzene in 3 ml. concentrated hydrochloric acid is treated with a solution of 6 g. stannous chloride in 6 ml. concentrated hydrochloric acid on the steam bath for 5 minutes. The mixture is cooled, decanted and the residue washed with 6 ml. 6N hydrochloric acid. The residue is treated with potassium bicarbonate and chloroform, filtered, and the chloroform layer repeated and dried over magnesium sulfate. Evaporation leaves 1,2-diamino-4-(p-chlorophenoxy)-benzene as a gum.

Workup

  1. temperatureThe mixture is cooled
  2. customdecanted
  3. washthe residue washed with 6 ml
  4. additionThe residue is treated with potassium bicarbonate and chloroform
  5. filtrationfiltered
  6. dry with materialdried over magnesium sulfate
  7. customEvaporation

Sources & evidence

ORD record
ord-93393df5bf4b47419253a9152ed57789
Source dataset
uspto-grants-1976_06
Patent number
US03965113

Reaction notes

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