Methyl formate → HCID 70637047, compound

HRID 1658721Notes

Reaction equation

HRID 1658721 reaction equation
COC=O.C(O)(=O)/C=C/C(O)=O.[CH3:13][N:14]([CH2:16][CH:17]1[CH2:35][CH2:34][N:20]2[C:21]3[CH:33]=[CH:32][CH:31]=[CH:30][C:22]=3[CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=3[CH:19]2[CH2:18]1)[CH3:15]>CO.CC(C)=O>[CH3:15][N:14]([CH2:16][CH:17]1[CH2:35][CH2:34][N:20]2[C:21]3[CH:33]=[CH:32][CH:31]=[CH:30][C:22]=3[CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=3[CH:19]2[CH2:18]1)[CH3:13]

Participants

4

Reactant 2

HCID 7865Methyl formateHCID 86733599HCID 86733599, compound

Product 1

HCID 70637047HCID 70637047, compound

Reagents, catalysts & solvents 1

HCID 21894497Aceton-methanolSolvent

Procedure

The above-mentioned product is treated with methylformate in the same way once again (melting point N-formyl-N-methylamino-methyl compound: 117°-119°C) and reduced after that. Obtained in this manner: 3.4 g. Melting point (ax.): 2-dimethylaminomethyl-1,2,3,4,10,14b-hexahydro-pyridino[1,2-a]-dibenzo[c,f]-azepine fumarate: 174°-176°C. Rf in methanol:acetone (9:1) = 0.40 on SiO2.

Workup

  1. customObtained in this manner
  2. custom174°-176°C

Sources & evidence

ORD record
ord-6c324d8192324766af1ecab2ac0d3603
Source dataset
uspto-grants-1976_06
Patent number
US03966723

Reaction notes

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