反应详情

4-Butylamino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester is treated with sodium hydroxide in ethanol for 20 hours at room temperature. The solvent is removed in vacuo and the residue is dissolved in water. On acidification with acetic acid, 4-butylamino-1H-pyrazolo[3,4-b]pyridine-5-caboxylic acid solidifies and is filtered off. The product is purified by recrystallization from acetic acid.

1. customThe solvent is removed in vacuo
2. dissolutionthe residue is dissolved in water
3. filtrationis filtered off
4. customThe product is purified by recrystallization from acetic acid