HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-Butylamino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-butylamino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester | HCID 53782720 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Butylamino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid | HCID 21514300 | — |
Reaction Steps
4-Butylamino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester is treated with sodium hydroxide in ethanol for 20 hours at room temperature. The solvent is removed in vacuo and the residue is dissolved in water. On acidification with acetic acid, 4-butylamino-1H-pyrazolo[3,4-b]pyridine-5-caboxylic acid solidifies and is filtered off. The product is purified by recrystallization from acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966746 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-3dc066806c0d4d9991660fa032b9ed9e |
| Source note | uspto-grants-1976_06 |