反应详情

α-trichloromethyl-p-chlorobenzyl alcohol, 5.0g, was stirred with p-chlorophenol, 2.6g, and sulfuric acid, 35 ml, was added dropwise. After 2 hrs. of stirring, the mixture was poured onto ice and extracted with ether. After drying with sodium sulfate, the ether was removed under vacuum and the residue was recrystallized from ethanol to give α-trichloromethyl-p-chlorobenzyl p-chlorophenyl ether, mp 101°C. This method of synthesis is referred to in Table I as method A.

1. additionwas added dropwise
2. additionthe mixture was poured onto ice
3. extractionextracted with ether
4. dry with materialAfter drying with sodium sulfate
5. customthe ether was removed under vacuum
6. customthe residue was recrystallized from ethanol