Imidazole → 3-(4-Benzyloxy-2,6-dichloro-benzyl)-1-[cis-4-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-pyrrolidin-2-one
Reaction equation
[C:31]([CH3:32])([CH3:33])([CH3:34])[Si:35]([CH3:36])([CH3:37])[Cl:38].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:30])[c:12]([CH2:13][CH:14]2[C:15](=[O:26])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:27]([Cl:29])[cH:28]1.[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[nH:39]1[cH:40][cH:41][n:42][cH:43]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:30])[c:12]([CH2:13][CH:14]2[C:15](=[O:26])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][Si:35]([C:31]([CH3:32])([CH3:33])[CH3:34])([CH3:36])[CH3:37])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:27]([Cl:29])[cH:28]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d3071afa099743b19458e4a140950a3f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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