HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-(2-Chlorophenyl)cinnamic acid → beta-(2'-Chloro-4-biphenylyl)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-(2-Chlorophenyl)cinnamic acid | HCID 54534814 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | beta-(2'-Chloro-4-biphenylyl)propionic acid | HCID 1394276 | — |
Reaction Steps
A suspension of 100 g of p-(2-chlorophenyl)cinnamic acid in 1 l. of 95% ethanol is hydrogenated at atmospheric pressure using platinum oxide catalyst (1 g). The uptake of hydrogen ceases when approximately 9-10 l. of hydrogen is consumed. The catalyst is then filtered off and the reaction evaporated to dryness to give β-(2'-chloro-4-biphenylyl)propionic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966801 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-828198b8ce5a45dc8b17d5737e10150b |
| Source note | uspto-grants-1976_06 |