Hydrochloric Acid → HCID 21525994, compound

HRID 1659082Notes

Reaction equation

HRID 1659082 reaction equation
Cl[CH:2]([CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[Cl:20])=[CH:10][CH:9]=1)[C:3]([OH:5])=[O:4].[SH-:21].[Na+].Cl>C(O)C>[SH:21][CH:2]([CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[Cl:20])=[CH:10][CH:9]=1)[C:3]([OH:5])=[O:4]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 28015Sodium hydrosulfideHCID 21525974HCID 21525974, compound

Product 1

HCID 21525994HCID 21525994, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 0.05 moles of α-chloro-γ-(2'-chloro-4-biphenylyl) butyric acid and 5 g. of sodium hydrosulfide in 100 ml. of absolute ethanol and under a nitrogen atmosphere is stirred for 15 hours. The mixture is then acidified with 6 N hydrochloric acid. The solvent is removed in vacuo and the residue is extracted into ether, washed with water, saturated sodium chloride solution, dried and evaporated to dryness to obtain α-mercapto-γ-(2'-chloro-4-biphenylyl)butyric acid.

Workup

  1. customThe solvent is removed in vacuo
  2. extractionthe residue is extracted into ether
  3. washwashed with water, saturated sodium chloride solution
  4. customdried
  5. customevaporated to dryness

Sources & evidence

ORD record
ord-0c6342c658dd45a79d7bd1e318319be4
Source dataset
uspto-grants-1976_06
Patent number
US03966801

Reaction notes

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