Potassium Hydroxide → HCID 21526657, compound

Participants

Reaction Steps

To 17.4 ml. of 2N alcoholic potassium hydroxide solution (0.035 mole) is added 4.84 g. (0.035 mole) of thiobenzoic acid. The solution is cooled to room temperature and to this is added in small portions 0.035 mole of α-chloro-γ-(2'-chloro-4-biphenylyl)butyric acid. The reaction mixture is stirred at room temperature for 25 hours, then the solvent is removed, the residue dissolved in ether, filtered and washed with cold water. The ethereal solution is then dried over magnesium sulfate and evaporated to dryness to obtain α-benzoylthio-γ-(2'-chloro-4-biphenylyl)butyric acid.

Provenance & Evidence