Water → HCID 178467559, compound

Participants

Reaction Steps

To a mixture of 32 g. (0.1 m.) of 3-(4'-chlorophenyl)-5-(1'-ethoxyethylidene)-rhodanine in 400 ml. of water and 250 ml. of methanol is added 85 ml. of 5% sodium hydroxide solution and the resulting suspension is stirred at room temperature for 5 hours. The reaction mixture is filtered and the filtrate is decolorized, then acidified with dilute hydrochloric acid to give 3-(4'-chlorophenyl)-5-(1'-hydroxyethylidene)-rhodanine, m.p. 200°-205°C.

Provenance & Evidence