Ethanol → HCID 178460826, compound

HRID 1659103Notes

Reaction equation

HRID 1659103 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11](=[C:14](OCC)[CH2:15][CH3:16])[S:10][C:9]2=[S:20])=[CH:4][CH:3]=1.C(O)C.[S-2:24].[Na+].[Na+]>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11](=[C:14]([SH:24])[CH2:15][CH3:16])[S:10][C:9]2=[S:20])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 14804Sodium SulfideHCID 86733629HCID 86733629, compound

Product 1

HCID 178460826HCID 178460826, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To a suspension of 3 g. (0.091 m.) of 3-(4'-chlorophenyl)-5-(1'-ethoxypropylidene)-rhodanine in 15 ml. of ethanol is added a solution of sodium sulfide in 10 ml. of water and the mixture is stirred at room temperature until solution is complete (15-20 minutes). This solution is added to 100 ml. of water, allowed to stand for 15 minutes, filtered and the filtrate is acidified with 2N hydrochloric acid to give 3-(4'-chlorophenyl)-5-(1'-mercaptopropylidene)-rhodanine, m.p. 163°-165°C.

Workup

  1. additionTo a suspension of 3 g
  2. custom(15-20 minutes)
  3. additionThis solution is added to 100 ml
  4. filtrationfiltered

Sources & evidence

ORD record
ord-2b35263a1dc24f3396e833e778fae63d
Source dataset
uspto-grants-1976_06
Patent number
US03966942

Reaction notes

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