Acetic Anhydride → HCID 86733634, compound

HRID 1659107Notes

Reaction equation

HRID 1659107 reaction equation
[C:1]1([N:7]2[C:11](=[O:12])[CH2:10][S:9][C:8]2=[S:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:14]([O:16][C:17](OCC)(OCC)[CH2:18][CH3:19])[CH3:15].C(OC(=O)C)(=O)C>>[CH2:14]([O:16][C:17](=[C:10]1[S:9][C:8](=[S:13])[N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:11]1=[O:12])[CH2:18][CH3:19])[CH3:15]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 66995Ethyl orthopropionateHCID 738224-Thiazolidinone, 3-phenyl-2-thioxo-

Product 1

HCID 86733634HCID 86733634, compound

Procedure

A mixture of 8.4 g. (0.04 m.) of 3-phenylrhodanine, 21 g. (0.12 m.) of triethylorthopropionate and 80 ml. of acetic anhydride is heated under reflux for six hours, cooled and filtered. The solid is washed with 50% aqueous acetic acid to afford 5-(1'-ethoxypropylidene)-3-phenylrhodanine, m.p. 178°-181°C.

Workup

  1. additionA mixture of 8.4 g
  2. temperatureunder reflux for six hours
  3. temperaturecooled
  4. filtrationfiltered
  5. washThe solid is washed with 50% aqueous acetic acid

Sources & evidence

ORD record
ord-25d833ba28b94deb89be58210eb699b1
Source dataset
uspto-grants-1976_06
Patent number
US03966942

Reaction notes

Loading…