Acetic Anhydride → HCID 178467560, compound

HRID 1659108Notes

Reaction equation

HRID 1659108 reaction equation
S1CC(=O)NC1=S.C(C(CC)(CC)C([O-])([O-])[O-])C.C(OC(=O)C)(=O)C.C([O:28][C:29](=[C:31]1[S:35][C:34](=[S:36])[N:33]([C:37]2[CH:42]=[CH:41][C:40]([F:43])=[CH:39][CH:38]=2)[C:32]1=[O:44])[CH3:30])C>>[F:43][C:40]1[CH:39]=[CH:38][C:37]([N:33]2[C:32](=[O:44])[C:31](=[C:29]([OH:28])[CH3:30])[S:35][C:34]2=[S:36])=[CH:42][CH:41]=1

Participants

5

Reactant 4

HCID 7918Acetic AnhydrideHCID 1201546RhodanineHCID 21875354TriethylorthoaceateHCID 86733635HCID 86733635, compound

Product 1

HCID 178467560HCID 178467560, compound

Procedure

Similar reaction of this rhodanine (0.2 m.) with 140 g. (0.86 m.) of triethylorthoacetate in 350 ml. of acetic anhydride followed by alkaline hydrolysis of the intermediate 5-(1'-ethoxyethylidene)-3-(4'-fluorophenyl)-rhodanine gives the corresponding 3-(4'-fluorophenyl)-5-(1'-hydroxyethylidene)-rhodanine.

Sources & evidence

ORD record
ord-1c17c06393fe4356abc6e457691db2fb
Source dataset
uspto-grants-1976_06
Patent number
US03966942

Reaction notes

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