Hydrochloric Acid → 2-methoxy-N-methyl-2-(2-pyridyl)thioacetamide hydrochloride

HRID 1659126Notes

Reaction equation

HRID 1659126 reaction equation
[CH3:1][O:2][CH:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)[C:4]([NH:6][CH3:7])=[S:5].[ClH:14]>CCOCC>[ClH:14].[CH3:1][O:2][CH:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)[C:4]([NH:6][CH3:7])=[S:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15581955HCID 15581955, compound

Product 1

HCID 214868942-methoxy-N-methyl-2-(2-pyridyl)thioacetamide hydrochloride

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

2-Methoxy-N-methyl-2-(2-pyridyl)thioacetamide (500 mg.) in ether is added to ethereal hydrogen chloride. The resulting precipitate is filtered off and recrystallized from ethanol/ether to give 2-methoxy -N-methyl-2-(2-pyridyl)thioacetamide hydrochloride.

Workup

  1. filtrationThe resulting precipitate is filtered off
  2. customrecrystallized from ethanol/ether

Sources & evidence

ORD record
ord-127840f35e5846239719a8259a75b71f
Source dataset
uspto-grants-1976_06
Patent number
US03966945

Reaction notes

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