4-Bromotoluene → HCID 54035029, compound

HRID 1659312Notes

Reaction equation

[CH2:1]([O:3][C:4](=O)[CH2:5][N:6]([CH3:8])[CH3:7])[CH3:2].Br[C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1>>[CH3:7][N:6]([CH2:5][CH:4]1[CH2:14][CH:15]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)[C:16]2[C:1](=[CH:2][CH:13]=[CH:12][CH:11]=2)[O:3]1)[CH3:8]

Participants

Reactant 2

HCID 78054-Bromotoluene

HCID 118412Glycine, N,N-dimethyl-, ethyl ester

Product 1

HCID 54035029HCID 54035029, compound

Procedure

The process of example 4 was repeated using N,N-dimethylglycine ethyl ester in place of the N,N-dimethylalanine ethyl ester in part (a), and using 4-bromotoluene in place of the 4-bromochlorobenzene in part (c) to yield the title compound, m.p. 114°-116° C.

Sources & evidence

ORD record: ord-a49485224b5440519f7fb25977de0eb7
Source dataset: uspto-grants-1981_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04303656

Reaction notes

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